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Thursday, July 5, 2012
European Parliament Declares Feared International Copyright Agreement Dead [Privacy]
Wednesday, July 4, 2012
Deena from 'Jersey Shore': I didn't use sidewalk
"Jersey Shore" cast member Deena Cortese, center, walks with her attorney Michael Pappa, left, in court after a hearing Tuesday, July, 3, 2012, in Seaside Heights, N.J. The "Jersey Shore" cast member was in Seaside Heights municipal court on a change of interfering with traffic for an incident in which police say she was dancing in a street and blocking the flow of traffic. Cortese pleaded guilty to failing to use the sidewalk and paid a $106 fine.(AP Photo/Mel Evans)
"Jersey Shore" cast member Deena Cortese, center, walks with her attorney Michael Pappa, left, in court after a hearing Tuesday, July, 3, 2012, in Seaside Heights, N.J. The "Jersey Shore" cast member was in Seaside Heights municipal court on a change of interfering with traffic for an incident in which police say she was dancing in a street and blocking the flow of traffic. Cortese pleaded guilty to failing to use the sidewalk and paid a $106 fine.(AP Photo/Mel Evans)
"Jersey Shore" cast member Deena Cortese walks from court after a hearing Tuesday, July, 3, 2012, in Seaside Heights, N.J. The Cortese was in Seaside Heights municipal court on a change of interfering with traffic for an incident in which police say she was dancing in a street and blocking the flow of traffic. She pleaded guilty to failing to use the sidewalk and paid a $106 fine. (AP Photo/Mel Evans)
"Jersey Shore" cast member Deena Cortese, right, stands with her attprney Michael Pappa, center back, during a hearing Tuesday, July, 3, 2012, in Seaside Heights, N.J. Police arrested Cortese on June 10, saying she was dancing in a roadway and interfering with the flow of traffic. But municipal prosecutor Kim Pascarella said the prosecution did not have enough evidence to prove that charge, agreeing instead to allow her to plead guilty to the lesser offense of not using a sidewalk when one was provided. She pleaded guilty to failing to use the sidewalk and paid a $106 fine. (AP Photo/Mel Evans)
"Jersey Shore" cast member Deena Cortese, right, adjusts a necklace for her mother, Joann Cortese, as they wait in court Tuesday, July, 3, 2012, in Seaside Heights, N.J. Police arrested Cortese on June 10, saying she was dancing in a roadway and interfering with the flow of traffic. But municipal prosecutor Kim Pascarella said the prosecution did not have enough evidence to prove that charge, agreeing instead to allow her to plead guilty to the lesser offense of not using a sidewalk when one was provided. She pleaded guilty to failing to use the sidewalk and paid a $106 fine. (AP Photo/Mel Evans)
As attorney Michael Pappa, left, looks on "Jersey Shore" cast member Deena Cortese, center, listens to her mother, Joann Cortese, right, and father John Cortese, second right, outside court after a hearing Tuesday, July, 3, 2012, in Seaside Heights, N.J. Cortese was in Seaside Heights municipal court on a change of interfering with traffic for an incident in which police say she was dancing in a street and blocking the flow of traffic. She pleaded guilty to failing to use the sidewalk and paid a $106 fine. (AP Photo/Mel Evans)
SEASIDE HEIGHTS, N.J. (AP) ? "Jersey Shore" cast member Deena Cortese got a costly reminder Tuesday of a lesson parents tell their children: Make sure you stay on the sidewalk.
And just to underscore that point, she got a talking-to from her mother outside municipal court, where Cortese had just pleaded guilty to failing to use the sidewalk and paid a $106 fine.
"He doesn't want to see you in that courtroom again," Deena's mom, Joann Cortese, said, referring to the judge who had imposed the fine. Then they hugged and kissed goodbye ? on the sidewalk.
"Love you," her mom said.
"Love you, too," Deena replied.
The pint-sized reality star also had to pay $33 in court costs but avoided a criminal conviction by pleading guilty to a violation of the motor vehicle code.
Police arrested her on June 10, saying she was dancing in a roadway and interfering with the flow of traffic. But municipal prosecutor Kim Pascarella said the prosecution did not have enough evidence to prove that charge, agreeing instead to allow her to plead guilty to the lesser offense of not using a sidewalk when one was provided.
"I'm sorry if I caused any trouble," Cortese said, standing before the same bench where co-star Nicole "Snooki" Polizzi pleaded guilty to disturbing other beachgoers in 2010.
Municipal Court Judge Dan Sahin gently rebuked Cortese for diverting police officers from more pressing concerns.
"Ms. Cortese, please keep in mind you're taking police officers away from a job they have to do," the judge said. Responding to the call, investigating, arresting her and bringing her back to police headquarters all took valuable time that could have better been spent serving others who needed help, he added.
"The officers here are not the New York City Police Department; we're not 1,000-strong," Sahin said. "They've got a tough job to do."
Cortese hugged her mother and wiped away a few tears as she waited in line with her lawyer, Michael Pappa, to pay the fine at the court clerk's window.
Pappa noted that the police report stated that Cortese appeared to have been drinking before the incident. On her personal website, Cortese calls herself "The Blast In A Glass."
"Deena was in the middle of the road," Pappa told The Associated Press. "Traffic was at a standstill because of summer congestion. She knew she made a mistake and she regrets what she did.
"She took this situation very seriously," he said. "She was very upset about getting arrested and having to go to the police station, and she was very apologetic to the police officers."
The judge also chided Cortese for endangering herself and others by her conduct.
"By going into traffic as she did, she placed herself in harm's way and quite possibly placed others in harm's way," Sahin said.
It was at least the third legal run-in that a "Jersey Shore" cast member has endured since the show began filming in Seaside Heights in 2009.
In addition to Polizzi's tipsy traipsing through the sand in 2010, Ronnie Ortiz-Magro was shown in an episode from the show's first season that generated an assault charge. Another man was shown taunting Ortiz and other cast members as they walked home, only to be laid out by a single punch from Ortiz-Magro, who boasted: "That's one shot! That's one shot, kid!"
Ortiz-Magro was originally charged with aggravated assault but entered a pre-trial intervention program that let him avoid criminal prosecution.
A native of the New Egypt section of New Jersey's Plumsted township, Cortese is a longtime friend of Polizzi, and joined the cast in its third season following the departure of cast member Angelina Pivarnick.
The cast is nearing the end of its sixth season of filming in and around Seaside Heights.
___
Wayne Parry can be reached at http://twitter.com/WayneParryAC
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Tufts Medical Center researchers receive $10 million NIH grant to test blood clot prevention drug
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Contact: Julie Jette
jjette@tuftsmedicalcenter.org
617-636-3265
Tufts Medical Center
Boston, Mass. (July 3, 2012) Tufts Medical Center researchers are developing a first-of-its-kind drug to prevent deadly blood clots in heart disease patients, without the risk of serious bleeding associated with current medications. The National Heart, Lung, and Blood Institute of the National Institutes of Health has just awarded the team led by Athan Kuliopulos, MD, PhD, a $10 million grant to start testing a drug based on this novel technology.
"If our study works, it's potentially game-changing and could become part of the standard of care for patients being treated for coronary artery blockages," said Kuliopulos, Director of the Hemostasis and Thrombosis Lab at Tufts Medical Center.
Heart disease is the leading cause of death in the United States. The new approach could benefit patients who have had heart attacks or who need cardiac catheterization procedures to prop open clogged arteries with a stent. These patients face increased risk for blood clots that can cause heart attack and death. To reduce these risks, patients are currently treated with anti-clotting drugs, which increase their risk of life-threatening bleeding problems.
In a study to be published today in the journal Circulation, Tufts Medical Center researchers have discovered a mechanism to inhibit the ability of platelets to form clots without increasing the risk of bleeding. The new approach uses pepducins, which are able to travel inside cells to block receptors and inhibit molecular pathways that stimulate clot formation. By contrast, most approved drugs block receptors on the outside of cells. If successful, this new strategy could lead to an entirely new class of drugs.
The pepducin, PZ-128, inhibits PAR1, a platelet protein that stimulates clotting. When added to human blood samples, PZ-128 appears to inhibit clotting without affecting bleeding markers. It also clears out of the blood stream within hours, which should reduce the risk of long-term bleeding problems.
"Anytime you have a new molecule that exploits a novel mechanism of action, it's very exciting and the benefit to patients is potentially tremendous,'' said Carey Kimmelstiel, MD, Director of the Cardiac Catheterization Laboratory and Interventional Cardiology at Tufts Medical Center. "A new technology that can inhibit platelet function without increasing bleeding would be enormously powerful."
The next step is to evaluate the safety and effectiveness of the pepducin in humans. The five-year, $10 million NIH grant will fund the early stages of drug development. Researchers will first conduct a Phase I clinical trial in healthy human volunteers to determine whether the drug is safe. If successful, the grant will cover a multi-center Phase II clinical trial in 800 patients.
The research is the result of a long-term collaborative effort between laboratory scientists and the clinicians in the Cardiac Catheterization Laboratory at Tufts Medical Center.
"These exciting advances would not have been possible without this strong partnership," said Kuliopulos. "It is critical for researchers to have an understanding and appreciation of the clinical issues and practical matters concerning the real-world application of the drug."
###
About Tufts Medical Center and Floating Hospital for Children
Tufts Medical Center is an exceptional, not-for-profit, 415-bed academic medical center that is home to both a full-service hospital for adults and Floating Hospital for Children. Conveniently located in downtown Boston, the Medical Center is the principal teaching hospital for Tufts University School of Medicine. Floating Hospital for Children is the full-service children's hospital of Tufts Medical Center and the principal pediatric teaching hospital of Tufts University School of Medicine. Tufts Medical Center is affiliated with seven community hospitals and with New England Quality Care Alliance, its community physicians' network. For more information, please visit www.tuftsmedicalcenter.org.
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?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
[ | E-mail | Share ]
Contact: Julie Jette
jjette@tuftsmedicalcenter.org
617-636-3265
Tufts Medical Center
Boston, Mass. (July 3, 2012) Tufts Medical Center researchers are developing a first-of-its-kind drug to prevent deadly blood clots in heart disease patients, without the risk of serious bleeding associated with current medications. The National Heart, Lung, and Blood Institute of the National Institutes of Health has just awarded the team led by Athan Kuliopulos, MD, PhD, a $10 million grant to start testing a drug based on this novel technology.
"If our study works, it's potentially game-changing and could become part of the standard of care for patients being treated for coronary artery blockages," said Kuliopulos, Director of the Hemostasis and Thrombosis Lab at Tufts Medical Center.
Heart disease is the leading cause of death in the United States. The new approach could benefit patients who have had heart attacks or who need cardiac catheterization procedures to prop open clogged arteries with a stent. These patients face increased risk for blood clots that can cause heart attack and death. To reduce these risks, patients are currently treated with anti-clotting drugs, which increase their risk of life-threatening bleeding problems.
In a study to be published today in the journal Circulation, Tufts Medical Center researchers have discovered a mechanism to inhibit the ability of platelets to form clots without increasing the risk of bleeding. The new approach uses pepducins, which are able to travel inside cells to block receptors and inhibit molecular pathways that stimulate clot formation. By contrast, most approved drugs block receptors on the outside of cells. If successful, this new strategy could lead to an entirely new class of drugs.
The pepducin, PZ-128, inhibits PAR1, a platelet protein that stimulates clotting. When added to human blood samples, PZ-128 appears to inhibit clotting without affecting bleeding markers. It also clears out of the blood stream within hours, which should reduce the risk of long-term bleeding problems.
"Anytime you have a new molecule that exploits a novel mechanism of action, it's very exciting and the benefit to patients is potentially tremendous,'' said Carey Kimmelstiel, MD, Director of the Cardiac Catheterization Laboratory and Interventional Cardiology at Tufts Medical Center. "A new technology that can inhibit platelet function without increasing bleeding would be enormously powerful."
The next step is to evaluate the safety and effectiveness of the pepducin in humans. The five-year, $10 million NIH grant will fund the early stages of drug development. Researchers will first conduct a Phase I clinical trial in healthy human volunteers to determine whether the drug is safe. If successful, the grant will cover a multi-center Phase II clinical trial in 800 patients.
The research is the result of a long-term collaborative effort between laboratory scientists and the clinicians in the Cardiac Catheterization Laboratory at Tufts Medical Center.
"These exciting advances would not have been possible without this strong partnership," said Kuliopulos. "It is critical for researchers to have an understanding and appreciation of the clinical issues and practical matters concerning the real-world application of the drug."
###
About Tufts Medical Center and Floating Hospital for Children
Tufts Medical Center is an exceptional, not-for-profit, 415-bed academic medical center that is home to both a full-service hospital for adults and Floating Hospital for Children. Conveniently located in downtown Boston, the Medical Center is the principal teaching hospital for Tufts University School of Medicine. Floating Hospital for Children is the full-service children's hospital of Tufts Medical Center and the principal pediatric teaching hospital of Tufts University School of Medicine. Tufts Medical Center is affiliated with seven community hospitals and with New England Quality Care Alliance, its community physicians' network. For more information, please visit www.tuftsmedicalcenter.org.
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?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-07/tmc-tmc070212.php
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EU's Barroso lashes out at British euro-sceptics
[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]
[ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]
Source: http://news.yahoo.com/eus-barroso-lashes-british-euro-sceptics-175851376.html
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Tuesday, July 3, 2012
Visit the Oval Office ... at an Oregon airport
Courtesy of Rogue Valley International-Medford Airport
This version of the White House's Oval Office can be rented out. Photo ops, anyone?
By Harriet Baskas, msnbc.com contributor
A southern Oregon airport that drew heat last year for a plan to sell advertising space on its control tower is back with a new money-making scheme.
The Rogue Valley International-Medford Airport has transformed an empty room in its terminal into a meeting room that looks just like the Oval Office at the White House in Washington, D.C.
The oval-shaped room, which includes draperies, flooring, an antique clock and furniture patterned after images of the Oval Office that airport officials found on the Internet, will be rented out for meetings, ceremonies, weddings and photo ops.
?We?re in a small community and we operate as a business, without any local tax funds,? airport director Bern Case told msnbc.com. ?So we hope this Oval Office idea will generate some dollars, add some culture and history to our community and give people something to do.?
Case said 25 area businesses and organizations participated in furnishing the room, which includes wood flooring in the same pattern currently in the real Oval Office and graphic wall coverings that include ?doors? and ?windows? that lead into private offices and look out onto the White House Rose Garden. The Resolute Desk?is a version once used for a play performed at the Oregon Shakespeare Festival in Ashland, Ore., about 15 miles away.
?The completed room is pretty close to the original, without being the precise dimensions,? said Case.
Rates to rent the faux Oval Office will be $75 for four hours and $25 for a 15-minute photo op session. Anyone showing up at the airport?s Open House on July 4?dressed as a current or former president or first lady will get one free use of room and be entered in a contest for two round-trip tickets from Medford to Los Angeles.
Airports Council International - North America, the trade association for North American airports, knows of no other airport with a replica of the Oval Office for rent. ?But airports continue to look for unique opportunities to enhance non-aeronautical revenue while improving the passenger experience across the United States and Canada,? said Debby McElroy, ACI-NA executive vice president for policy and external affairs.
While some airports are earning revenue from activities such as on-site pet hotels and land leases for farming and oil-drilling, last year the Rogue Valley International-Medford Airport had to nix its plan to rent out space on its 100-foot-tall control tower due to local dissent over the plan.
?That was a bit controversial,? said Case, ?but the Oval Office is approved and ready to go.?
Find more by Harriet Baskas on StuckatTheAirport.com and follow her on Twitter.?
More stories on Itineraries
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?
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Study sheds light on pregnancy complications and overturns common belief
ScienceDaily (July 3, 2012) ? A study led by Hospital for Special Surgery researchers has demonstrated that women who have a specific type of antibody that interferes with blood vessel function are at risk for adverse pregnancy outcomes and that other antibodies in the same family thought to cause pregnancy complications do not put women at risk.
The researchers say that many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin injections, which can cause bleeding and bone loss. The multicenter study appears in the July 2012 issue of the journal Arthritis & Rheumatism.
"This paper identifies people who are at risk for pregnancy loss and, more importantly, those who are not at risk and who therefore do not need to be treated," said Michael Lockshin, M.D., director, Barbara Volcker Center for Women and Rheumatic Disease, and co-director, Mary Kirkland Center for Lupus Research at Hospital for Special Surgery (HSS), New York City, and lead author of the study.
Antiphospholipid antibodies interfere with phospholipids, a type of fat found in all living cells and cell membranes, including blood cells and the lining of blood vessels. Patients with these antibodies are at risk for blood clots, stroke, and pregnancy complications, but some patients with these antibodies can be completely healthy. "Phospholipids are highly exposed in the placenta, and as a result antiphospholipid antibodies concentrate there," said Jane Salmon, M.D., the study's senior author and Collette Kean Research Chair and co-director, Mary Kirkland Center for Lupus Research at HSS. "When antibodies are deposited in a person's tissues, inflammation is initiated leading to organ damage." And this is a mechanism for pregnancy complications.
Women who have recurrent pregnancy loss are commonly tested for the presence of aPLs, and up to 15% are positive. Most patients who test positive are treated with anticoagulants. Currently, there are no standards regarding which aPLs doctors test for to assess risk (there are three main ones) and interlaboratory consistency of results is poor.
The new study is the first clinical research publication of the PROMISSE study, an ongoing multicenter, prospective clinical trial comparing the pregnancies of women with aPL, lupus, both aPL and lupus, and healthy controls. Between 20% and 35% of patients with lupus and aPL have pregnancy complications and the study is attempting to identify which patients are at risk.
"The identification of biomarkers that identify patients at high risk will allow us to select a subset of patients who we can consider in an interventional trial," said Dr. Salmon, the principal investigator of PROMISSE. This PROMISSE study, which involves over 700 patients from nine centers in North America, is funded by the National Institute of Arthritis, Musculoskeletal and Skin Diseases of the National Institutes of Health. A strength of PROMISSE is that all aPL tests were sent to core laboratories, eliminating interlaboratory variability.
The current analysis focused on 144 patients who had aPLs, of whom 28 had adverse pregnancy outcomes. A control group, 159 healthy pregnant women, was tested parallel to the group with aPLs. Controls were selected among women with no known illness, no prior fetal loss, no more than one miscarriage and at least one successful pregnancy.
The study examined the association between adverse pregnancy outcome and the presence of three different aPLs: lupus anticoagulant [LAC], anticardiolipin antibody [aCL] and antibody to ?2 glycoprotein I. An adverse pregnancy outcome was defined as otherwise unexplained fetal death after 12 weeks, neonatal death prior to discharge that was associated with complications of prematurity, preterm delivery prior to 34 weeks because of gestational hypertension, preeclampsia or placental insufficiency, and birthing a child that was small for its gestational age.
The researchers found that LAC was the strongest predictor of an adverse pregnancy outcome; 39% of patients with LAC had an adverse outcome compared to 3% who did not have LAC (P<0.0001). Only 8% of women with aCL, but not LAC, suffered an adverse outcome. Other aPLs did not increase risk. "Lupus anticoagulant is the most important predictor of risk and high titer anticardiolipin antibodies alone don't provide substantial risk," said Dr. Salmon. She noted that prior to this study, many physicians considered aCL as a potent predictor of risk.
Anticoagulant treatments are currently used for many women with aPLs, but identifying who to treat is not clear and this treatment is often ineffective. "Although many patients with aPLs are treated with heparin, pregnancy outcomes are still disappointing. We need better therapies," said Dr. Salmon. "This study will allow us to identify subsets of patients with the highest risk in whom to test new approaches and new drugs."
Dr. Salmon's studies in mice with aPL have shown that blocking inflammatory pathways can prevent miscarriages, growth restriction and preeclampsia. Further studies on samples from PROMISSE patients, followed by interventional trials will hopefully shed light on whether this therapeutic approach will be effective in pregnant women with aPLs and/or lupus.
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Story Source:
The above story is reprinted from materials provided by Hospital for Special Surgery, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Michael D. Lockshin, Mimi Kim, Carl A. Laskin, Marta Guerra, D. Ware Branch, Joan Merrill, Michelle Petri, T. Flint Porter, Lisa Sammaritano, Mary D. Stephenson, Jill Buyon, Jane E. Salmon. Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies. Arthritis & Rheumatism, 2012; 64 (7): 2311 DOI: 10.1002/art.34402
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/zZ-P1Hv-6oQ/120703200550.htm
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Feathered saurians -- downy dinosaur discovered
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Contact: Dr. Kathrin Bilgeri
kathrin.bilgeri@lmu.de
49-892-180-6938
Ludwig-Maximilians-Universitt Mnchen
The new fossil find from the chalk beds of the Franconian Jura evokes associations with a pet cemetery, for the young predatory dinosaur reveals clear traces of fluffy plumage. It also poses an intriguing question: Were all dinosaurs dressed in down?
The fossil of the fledgling saurian, probably newly hatched when it met its end, is remarkable in many ways. First of all, juveniles are extremely rare in the dinosaur fossil record, so every new discovery provides insights into dinosaur nurseries. Moreover, this specimen is perhaps the best-preserved predatory dinosaur that has yet been found in Europe. And Sciurimimus albersdoerferi, which lived during the Jurassic Period some 150 million years ago, displays one very striking feature its whole body must have been covered with a thick plumage of feathers.
All the feathered dinosaurs so far described belonged to the lineage that gave rise to modern birds. "However, Sciurumimus belongs to a much older branch of the family tree of predatory dinosaurs," says LMU paleontologist Dr. Oliver Rauhut, who is also affiliated with the Bavarian State Collection for Paleontology and Geology, and led the investigation into the structure and affinities of the sensational new find. "Its plumage may be telling us that all predatory dinosaurs had feathers."
Were all dinos decked out with feathers?
Several fossil finds have revealed that the pterosaurs which were capable of flight and are the closest relatives of the dinosaurs bore hair-like plumage on their bodies. Their fluffy coats resemble the downy feathers that can be recognized in the new fossil. This observation is very significant, as it suggests to the researchers that not just the pterosaurs and the predatory dinosaurs, but all dinosaurs may have had feathers. "If that is the case, we must abandon all our notions about giant reptiles encased in tough scales," Rauhut says.
As the German-American research team led by Rauhut has been able to show, the new specimen represents a young megalosaur. The genus name Sciurumimus means "squirrel-like" and refers to the animal's bushy tail, while the species designation albersdoerferi honors the private collector who made the fossil available for scientific study. "When the skeleton was irradiated with UV light, we were able to discern fragments of the skin and the plumage as fluorescent spots and filaments," says co-author Dr. Helmut Tischlinger.
Cute little dino kids
The juvenile Sciurumimus tells us even more. For instance, as in the case of other dinosaurs, its eyes were proportionately much larger than those of adult animals. In other words, young dinosaurs conformed to the "babyface" model. Secondly, it has long been suspected that not just the form of a dinosaur's face, but also its whole mode of life, was subject to change during lifetime. "And indeed, this individual has a very different set of teeth from those found in adult megalosaurs," says Rauhut. "That enables us to conclude that their diets also changed as they got older."
The young Sciurumimus, with its slender, pointed teeth probably preyed on insects and small animals. Fully grown megalosaurs, on the other hand, often exceeded 6 m in length and may have weighed more than a ton, and could give other large dinosaurs a good run for their money. That may also be true of the new species. "We know that dinosaurs were able to grow at terrific rates; diminutive hatchlings could reach adult lengths of several meters," Rauhut points out. "And even if they might have looked fluffy, they were certainly among the top predators in the food chain." (suwe)
###
The study was financially supported by the Volkswagen Foundation and the American Museum of Natural History.
Publication:
Exceptionally preserved juvenile megalosauroid theropod dinosaur with filamentous integument from the Late Jurassic of Germany
Oliver W. M. Rauhut, Christian Foth, Helmut Tischlinger, and Mark A. Norell
PNAS Early Edition
www.pnas.org/cgi/doi/10.1073/pnas.1203238109
Contact:
Dr. Oliver Rauhut
Bavarian State Collection for Paleontology and Geology
Richard-Wagner-Str. 10
80333 Mnchen
Phone: +49 89 2180 6645 / +49 163 741 7552
Email: o.rauhut@lrz.uni-muenchen.de
Or:
Dipl.-Biol. Christian Foth
Bavarian State Collection for Paleontology and Geology
Richard-Wagner-Str. 10
80333 Mnchen
Tel: +49 89 2180 6619
Email: christian.foth@yahoo.de
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Contact: Dr. Kathrin Bilgeri
kathrin.bilgeri@lmu.de
49-892-180-6938
Ludwig-Maximilians-Universitt Mnchen
The new fossil find from the chalk beds of the Franconian Jura evokes associations with a pet cemetery, for the young predatory dinosaur reveals clear traces of fluffy plumage. It also poses an intriguing question: Were all dinosaurs dressed in down?
The fossil of the fledgling saurian, probably newly hatched when it met its end, is remarkable in many ways. First of all, juveniles are extremely rare in the dinosaur fossil record, so every new discovery provides insights into dinosaur nurseries. Moreover, this specimen is perhaps the best-preserved predatory dinosaur that has yet been found in Europe. And Sciurimimus albersdoerferi, which lived during the Jurassic Period some 150 million years ago, displays one very striking feature its whole body must have been covered with a thick plumage of feathers.
All the feathered dinosaurs so far described belonged to the lineage that gave rise to modern birds. "However, Sciurumimus belongs to a much older branch of the family tree of predatory dinosaurs," says LMU paleontologist Dr. Oliver Rauhut, who is also affiliated with the Bavarian State Collection for Paleontology and Geology, and led the investigation into the structure and affinities of the sensational new find. "Its plumage may be telling us that all predatory dinosaurs had feathers."
Were all dinos decked out with feathers?
Several fossil finds have revealed that the pterosaurs which were capable of flight and are the closest relatives of the dinosaurs bore hair-like plumage on their bodies. Their fluffy coats resemble the downy feathers that can be recognized in the new fossil. This observation is very significant, as it suggests to the researchers that not just the pterosaurs and the predatory dinosaurs, but all dinosaurs may have had feathers. "If that is the case, we must abandon all our notions about giant reptiles encased in tough scales," Rauhut says.
As the German-American research team led by Rauhut has been able to show, the new specimen represents a young megalosaur. The genus name Sciurumimus means "squirrel-like" and refers to the animal's bushy tail, while the species designation albersdoerferi honors the private collector who made the fossil available for scientific study. "When the skeleton was irradiated with UV light, we were able to discern fragments of the skin and the plumage as fluorescent spots and filaments," says co-author Dr. Helmut Tischlinger.
Cute little dino kids
The juvenile Sciurumimus tells us even more. For instance, as in the case of other dinosaurs, its eyes were proportionately much larger than those of adult animals. In other words, young dinosaurs conformed to the "babyface" model. Secondly, it has long been suspected that not just the form of a dinosaur's face, but also its whole mode of life, was subject to change during lifetime. "And indeed, this individual has a very different set of teeth from those found in adult megalosaurs," says Rauhut. "That enables us to conclude that their diets also changed as they got older."
The young Sciurumimus, with its slender, pointed teeth probably preyed on insects and small animals. Fully grown megalosaurs, on the other hand, often exceeded 6 m in length and may have weighed more than a ton, and could give other large dinosaurs a good run for their money. That may also be true of the new species. "We know that dinosaurs were able to grow at terrific rates; diminutive hatchlings could reach adult lengths of several meters," Rauhut points out. "And even if they might have looked fluffy, they were certainly among the top predators in the food chain." (suwe)
###
The study was financially supported by the Volkswagen Foundation and the American Museum of Natural History.
Publication:
Exceptionally preserved juvenile megalosauroid theropod dinosaur with filamentous integument from the Late Jurassic of Germany
Oliver W. M. Rauhut, Christian Foth, Helmut Tischlinger, and Mark A. Norell
PNAS Early Edition
www.pnas.org/cgi/doi/10.1073/pnas.1203238109
Contact:
Dr. Oliver Rauhut
Bavarian State Collection for Paleontology and Geology
Richard-Wagner-Str. 10
80333 Mnchen
Phone: +49 89 2180 6645 / +49 163 741 7552
Email: o.rauhut@lrz.uni-muenchen.de
Or:
Dipl.-Biol. Christian Foth
Bavarian State Collection for Paleontology and Geology
Richard-Wagner-Str. 10
80333 Mnchen
Tel: +49 89 2180 6619
Email: christian.foth@yahoo.de
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-07/lm-fs-070312.php
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Kanye West And Pusha T Show Off Their 'New God Flow'
'Ye already debuted his verse during Sunday's BET Awards.
By Rob Markman
Kanye West performs at the 2012 BET Awards on Sunday
Photo: Michael Buckner/ Getty Images
Source: http://www.mtv.com/news/articles/1688956/kanye-west-pusha-t-new-god-love.jhtml
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Long, hot summer: Wildfires thrive on drought, heat and wind
The wildfires that have already destroyed more than 700 homes and outbuildings along Colorado's Front Range and blackened hundreds of thousands of acres of New Mexico wilderness are not likely to be the season's last for one simple reason: drought.
"This year, fires are going big," Tom Harbour, fire and aviation director for the U.S. Forest Service, said last week. "We've had some really extraordinary runs ? fires that are running 10 miles in lighter fuels. Fires that are running miles in forested areas."
PHOTOS: U.S. wildfires 2012
A dry La Nina winter and a paltry, quick-melting snowpack in much of the West have set the stage for another incendiary summer, compounding the effects of a long-term drought that has gripped the seven-state Colorado River basin for more than a decade.
"The reason Colorado is burning is they've had prolonged drought," said Bob Keane, a Forest Service research ecologist based in Montana. Add the high temperatures and gusting winds that hit the state last week, and you have a recipe for combustion.
Southern California is not immune. Officials are bracing for a higher fire danger after several years of respite from the catastrophic blazes that erupted over the last decade, including the 2009 Station fire, the largest in Los Angeles County history. Last winter, rainfall was well below average, leaving hills brown and dry even before summer began.
PHOTOS: Colorado Springs' Waldo Canyon fire
Still, federal officials do not expect this year to be as disastrous as 2002, when massive blazes exploded all around the West, including Colorado's largest ever, the 138,000-acre Hayman fire. Wetter conditions in the Pacific Northwest and parts of the northern Rocky Mountains should help ease the fire threat there.
Drought, rising temperatures, a century of fire suppression policies that allowed many forested areas to grow unnaturally thick with fuel, and more and more people living on the wilderness edge have thrust the West into this new era of bigger and fiercer burns. The amount of land charred every year has soared compared with previous decades.
Since 2000, it has not been uncommon for wildfire seasons to end with a tally of 7 million to 9 million blackened acres nationally. Though total burned acreage dropped during a few years of milder weather, it spiraled again last year when flames galloped across parched Texas.
Researchers predict that rising temperatures associated with climate change will lead to more wildfires in much of the West. But it is hard to tease out the effects of global warming from natural climate cycles, which in past centuries have seized the region with long, severe droughts.
"We've had conditions like this in the past," Keane said. "So you can't say with any degree of certainty ? that this is climate change. But what you can say is that it certainly meets the model of climate change."
As of Sunday, seven large fires in Colorado had charred a total of nearly 152,000 acres. None individually is as big as the Hayman was. But the Waldo Canyon fire west of Colorado Springs, which claimed two lives, and the High Park blaze in the mountains west of Fort Collins, now 100% contained, burned more than 700 structures, making them the most destructive in the state's history.
Colorado recognized the potential for a fiery summer, but "I don't think anyone was prepared" for what has occurred, said Chad Hoffman, co-director of the Western Forest Fire Research Center at Colorado State University at Fort Collins. Smoke from the High Park fire about 13 miles away shrouded the campus early last week and flames were visible on the horizon.
The Colorado blazes have raced across grass, shrub lands and timber, including ponderosa pine stands that are denser than they were historically. "There's a lot more fuel than there used to be," Hoffman said.
There are also a lot more houses. Though Harbour said Colorado had up-to-date fire prevention standards for new homes, older residences were not built with wildfires in mind, a situation throughout the West.
And whipping wind, triple-digit temperatures and dried-out fuel can make an inferno unstoppable until the weather changes. Rain came to the aid of firefighters in the High Park blaze, while cooler weather and rising humidity helped to calm the flames in Waldo Canyon, where the fire is now 45% contained.
All told, more than 1,500 structures have been lost to Western wildfires this season, including nearly 300 in Utah, 223 in Montana's Dahl fire and 254 in the Little Bear fire in New Mexico.
Far larger than the Colorado fires, the still-smoldering Whitewater-Baldy Complex fire in New Mexico destroyed only 20 structures because it has burned mostly in remote national forest lands, including the Gila Wilderness.
The Gila National Forest has also been a pioneer in using fire as a management tool, monitoring wildfires rather than rushing to put them out and using controlled burns to clean out younger, dense growth. An initial review of burn damage by the Forest Service suggests that approach has helped. Of the nearly 300,000 acres within the Whitewater-Baldy fire perimeter, slightly more than half burned lightly or not at all.
Prescribed fire and mechanical thinning of dense growth are crucial to making forest lands less vulnerable, Harbour said.
"It's that combination of having communities become fire adapted and improving the condition of the forest that is going to get us out of this death spiral of increasingly severe fire that we're in right now," he said.
bettina.boxall@latimes.com
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